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For high achievers, this can mean the death of self-esteem.
FORBES: 10 Myths About Successful Entrepreneurs -- Debunked
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Heading each chapter is a paragraph charting the terrible progress of the disease in a real family, and making the connection between the death of the cell and the death of the self.
ECONOMIST: When memory fails
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And although it may seem unimaginable that Hollywood could ever go the way of Detroit, whose greedy car workers and self-absorbed bosses were nearly the death of the American car industry, it is worth remembering how unimaginable it once was that Detroit could go the way of Detroit.
ECONOMIST: Star wars
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He concluded that on the balance of probabilities, the deaths of Ptes Benton, James and Gray were self-inflicted, but he offered no conclusion on the death of Pte Collinson, whose inquest returned an open verdict earlier this month.
BBC: NEWS | UK | The Deepcut investigations
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Republicans cannot get out of their death spiral unless they stage an intervention into the very roots of their self-image.
FORBES: Move up http://i.forbesimg.com t Move down
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We are unlikely to cease making gods or inventing ceremonies to please them for as long as we are afraid of death, or of the dark, and for as long as we persist in self-centeredness.
FORBES: Thoughts on the Business of Repentance, Yom Kippur and Dephlogistication
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The tragic death of Tunisian street vendor Mohamed Bouazizi, by self-immolation, brought about a grassroots political movement among Tunisians that effectively overthrew the country's authoritarian ruler, Zine el-Abidine Ben Ali.
CNN: Africa's rocky road to democracy
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At the time of Mr Fellows' death, Kovvali was working as a self-employed contractor for Primecare, a primary health care services provider.
BBC: Sheffield doctor jailed over diagnosis error
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The level of monitoring was gradually reduced and, the day before his death, Spiller told prison staff he had no thoughts of self-harm and was looking forward to his release.
BBC: Billy Spiller
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Inspectors, who visited after Mr Balogan's death, said they were pleased to see improvements in the management of vulnerable prisoners and that suicide and self-harm was "generally well managed".
BBC: Glen Parva sign