The shrinkage of the printed book business - particularly in non-fiction - has also led the publisher setting up ad-funded websites Honest John - for car enthusiasts, the Complete University Guide and home-grown veg site Allotments.

BBC: Ebooks: Is digital opening up a new chapter for publishing?

The team from Juntendo University in Tokyo is the first to publish a complete guide to its entire genetic structure.

BBC: Breakthrough in 'superbug' battle