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Thaxton admits he has got a lot more riding on the fight than the 30-year-old Frenchman.
BBC: Thaxton faces French challenger
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Hennessy said it is not just Thaxton's boxing talent that puts him in the line for titles.
BBC: Thaxton deserves world title shot
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Earl, 29, and British champion Jonathan Thaxton have both been touted to next face Commonwealth title holder Khan.
BBC: Earl eager to tie up Khan clash
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Thaxton, 34, is gearing up for his second shot at the European lightweight title against Juan Carlos Diaz Melero on 4 October.
BBC: Thaxton angles for shot at Khan
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But Thaxton expects the Olympic silver medallist to give Romanov a wide berth after his emphatic defeat by the European lightweight champion.
BBC: Romanov ends Thaxton's title bid
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Thaxton faces French champion Anthony Mezaache at the Norfolk Showground on Saturday, 28 February, and he told BBC Radio Norfolk it will not be easy.
BBC: Thaxton faces French challenger
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Thaxton, a veteran of 15 years as a professional fighter, is facing up to the fact that he is the rank outsider to win against Romanov.
BBC: Thaxton gets title shot incentive
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Thaxton has made no secret of his desire to test himself against Khan before he retires, but he admits he is still not sure if it will ever happen.
BBC: Thaxton angles for shot at Khan
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The Bolton fighter has previously avoided fighting Thaxton when he was made mandatory challenger to the British title, and again when Thaxton was declared the challenger to Khan's Commonwealth belt.
BBC: Thaxton angles for shot at Khan
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The defeat was veteran Thaxton's eighth in his 41-fight career but the Norwich fighter insisted afterwards he had no complaints with his corner's decision to withdraw him from the bout.
BBC: Romanov ends Thaxton's title bid
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Thaxton won the title with a third-round knockout of Juan-Carlos Diaz Melero at the Showground in October and Hennessy believes that his punching power would stand up to the world's best.
BBC: Thaxton deserves world title shot