Well thanks very much for your call Brian.

BBC

Dear Brian: Thanks for your question.

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The visitors could - and perhaps should - have been gunning for a Grand Slam, having beaten England, only to then draw with Ireland thanks to a late Brian O'Driscoll try and lose 9-8 to Scotland despite producing attacking statistics that suggested they should have won by around 30-40 points.

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Yet thanks to all of the new drugs, the median survival for patients has doubled over the last decade, according to Brian Durie, co-founder and chairman of the International Myeloma Foundation.

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