Their sheer size means that even a mundane problem could cause a systemic crisis or a bank run.
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Lung cancer is a systemic risk to a human body, but a smart insurer will not wait to change the premium until the first black spot appears on the X-ray.
That they are shoring up a firm too small to pose a systemic risk betrays a continuing lack of confidence in the financial system's ability to absorb even modest shocks.
Yet, the assumption of Cyprus not being a systemic risk rests on a single expectation: that it stays in the euro zone.
If banks suddenly lost confidence in government debt, the result could be both a systemic banking crisis and a funding crisis for the Japanese government.
Economists around the world talk of a systemic crisis, and predict a default by Greece or Italy would result in collapse of the euro zone and a severe recession in Europe that would engulf the entire global economy.
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Second, while creditors are insured against a systemic collapse they are not insured against a partial collapse.
Treasury Secretary Hank Paulson defended the move, saying Wachovia's failure would have posed a systemic risk, and that its sale prevented a "market disruption, " adding that the FDIC's action helped mitigate this risk, according to TradeTheNews.com.
Mr Oudea rejects the idea of a systemic failure, arguing that the loss was a product of a particular time and place: a period of rapid growth in equity derivatives, which overstretched the bank's capacity to monitor itself, and a peripheral trading desk where people were less jumpy about the risk of fraud.
As I've advocated, a similar systemic risk levy to finance a "resolution fund" is being considered in Congress as a way to internalize potential bailout costs stemming from too-big-to-fail institutions.
The EU and the UK seem to be avoiding a systemic solution to the present financial crisis in favor of a tactical cure.
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To hear Graham tell it, this is part of a systemic failure to address drug safety on the part of the FDA, a story that reaches back over the entirety of his 20-year career at the agency.
Even so, the worry is that a systemic regulator would be biased towards intervention, because it would face less criticism for puncturing a non-bubble than for failing to spot a real one.
It is more fundamentally a debate about systemic changes in the offing as a result of TARP.
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To that end, the Society of Actuaries and the Casualty Actuarial Society hosted a call for essays, " Systemic Risk, Financial Reform, and Moving Forward from the Financial Crisis, " seeking to find solutions that would prevent a future systemic meltdown.
Gmail is not a systemic innovation and Google Apps are kind of like other apps.
If quality was a problem, it was a systemic error and not connected to employee morale.
"This is a systemic failure, that's what this comes down to, " Mr. Littleton said.
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Why does everybody start talking about systemic risk after a crisis has already started?
The Tigers have never been docked a football scholarship for a systemic academic failing.
Despite all the benefits, Linenberg says systemic risk is a bigger concern than oil prices.
Why hadn't that been got right first, before redefining chronic care in a systemic way?
Unlike some Asian countries, the Mexicans acted relatively quickly to avoid a systemic collapse.
It has spread so far that there is now a real danger of a systemic collapse.
The politicians who dreamed up the directive talk about systemic risk, a concern for financial stability.
The business of business has the potential to make long-term, systemic social change a reality.
The government also gets new authority to take over and unwind foundering companies deemed a systemic risk.
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"At this stage it is not a sum of individual problems, it is a systemic problem, " he said.
He described it as an isolated case and said there was not a systemic problem at the prison.
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