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She says she chose Lake Ontario for her swim because it's one of the hardest open-water swims in the world, and she wanted to "accomplish something difficult" for children who fight cancer.
CNN: 14-year-old swims solo across Lake Ontario
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When he does not run or swim or bike for a couple of days, it unravels him a little.
WSJ: Jason Gay: Italian for Dinner, a Triathlon for Dessert
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One, a former diver with the Royal Navy who had been paralysed in a car accident, told Paul that it was impossible for them to swim on their fronts without their heads flopping into the water.
BBC: NEWS | Health | A bike for the paralysed
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The man was reassured when a surfer mentioned that it could have been someone acclimatising for a swim, the hearing was told.
BBC: Open verdict on Pauline Annette Edwards missing in 2010
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Nyad's team of more than 30 people consists of about 10 handlers, who will take turns minding Nyad's every move for the estimated 60 hours it will take her to complete this swim.
CNN: Nyad: Swim shows 60s 'not too late' for goals
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For outsiders though, it is hard not to wonder whether an icy swim simply replaces a Guinness-induced headache with a different kind of pain.
BBC: Dublin��s chilly tradition
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There is, however, another option, and it's one that isn't known for being found at swim-up bars across the world.
WSJ: Not Your Suburban Orange Julius
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They probably won't take down the drug Goliath--but they could make it harder for pharmaceutical giants to keep their heads above water as they swim from one blockbuster drug to the next.
FORBES: Could Many Davids Slay The Big Pharma Goliath?
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For sure, the Manhattan skyline is an exhilarating part of the swim, not least because it means the end of the marathon is near.
WSJ: N.Y.'s Tour de Hudson
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She hopes to attempt the swim in either August or September 2009, and her coach Sean Kelly says it is a welcome change for her after her Beijing exertions.
BBC: Patten aiming to swim the Channel