In this mix, products like Avinza (a sustained release morphine) and Eveda (an abuse resistant morphine) make a lot of sense the same sales reps can sell them.

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The study of a sustained release oral formulation of the synthetic form of prostacylin showed that patients treated for pulmonary arterial hypertension did not achieve a statistically significant improvement in how far they were able to walk within six minutes by week 16 of the trial.

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That represents not only Glucophage, but several other drugs, including a sustained-release version called Glucophage XR.

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Arteries in a group of patients given a sustained-release version of the stent didn't close at all.

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In the study where it helped patients lose weight, the drug also raised good cholesterol, or high-density lipoprotein (HDL), by 23%, almost as much as Niaspan, the sustained-release niacin drug made by Kos Pharmaceuticals (nasdaq: KOSP - news - people ) that is the main currently available treatment for raising HDL. Rimonabont also cut triglycerides, another risk factor for heart disease, by 16%.

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The chain sells the shoes at full price and, despite a weak economy and sustained high unemployment, often sells out of them on release days.

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Arnold says Glaxo already has managed to switch 30% of Paxil patients to Paxil CR, a controlled-release version that lasts longer and may deliver a more sustained dose.

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Now, if you had a combination therapy with nanoparticles, the drugs would slowly release into the tumor cells and you would have high, sustained levels of drug in the tumor.

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