He asked music lovers to identify passages of songs that reliably set off a physical reaction, such as tears or goose bumps.

WSJ: Why Adele's 'Someone Like You' Makes Everyone Cry

Now, the reality of another such tragedy tears at the heart of Dave Kane, whose 18-year-old son Nicky was the youngest victim of the Station fire.

CNN: STORY HIGHLIGHTS

And just as the maple syrup used to run freely, so now do our tears for such a monumental waste.

FORBES: School Shooting In Chardon, Ohio: 'A Quaint, Lonely Town'

Sarno realized that unresolved emotional issues and not physical abnormalities, such as bulging discs or muscular tears, were the cause of the pain outbreak sweeping the nation.

FORBES: How America's Best Pain Doctor - John Sarno - Took On The Medical Establishment and Won

Then over the next few days, miners were coming home to my village, Dowlais, in tears - I'd never seen such a sight.

BBC: 1966: Aberfan - a generation wiped out

While the promising results for Nexavar may bring tears to the eyes of Bayer researchers and hope to cancer patients, doctors have lately become used to such breakthroughs, with pharmaceutical giants like Pfizer, GlaxoSmithKline and AstraZeneca testing dozens of new targeted cancer pills.

FORBES: Magazine Article