The highlight is always the question-and-answer session with Buffett and his longtime partner Charlie Munger, and for the past few years Buffett has added wrinkles such as hosting journalists and analysts to ask questions alongside shareholder queries.

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Other wrinkles complicate response-time measurement, such as human error.

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Gupta: In 1989, long before physicians injected Botox into faces to smooth wrinkles, the FDA approved it for patients with debilitating neurological diseases such as dystonia.

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