The world rarely sees someone who has had such a profound impact on so many.
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"I consider myself lucky to have known Dave and to have experienced his music in such a profound way, " Clinton said.
It's these kind of skills - and others - that would have such a profound impact on teenagers' outlook on life.
But Turin's work challenged the status quo in such a profound way that smell specialists had a tough time believing he was correct.
The world rarely sees someone who made such a profound impact.
He says there are several possibilities: people may have considered it inappropriate for a woman to discuss Buddhist doctrine at such a profound level at the time or she may have thought that Buddhist doctrine should be independent of an individual.
But we live in a way that is just so isolated from one another and if you've ever experienced a form of intentional living where there's such a profound sense of community and of cooperation and love for one another, that is something I feel like we're really missing.
It was the first time a President had addressed the nation in such an intimate and informal way, and it had a profound impact.
Along with anything else that reminds a person of the trauma, these intrusive memories produce profound psychological distress and physical symptoms, such as a pounding heart.
Some noted French trends of the past such as Japonisme and Chinoiserie have made a profound impact on French culture.
Those seeking to explore such profound questions could not ask for a better guide than Mr Fletcher.
Music scholar and composer David Cope has built a machine which creates music of such profound artistic quality that it can even fool the experts.
There is very little chance that politicians would ever choose to use the model they developed in Cyprus in a country like Italy or Spain, where a run on the banks would have such profound implications.
At such a moment as this the assurances of support which we have received from the empire are a source of profound encouragement to us.
Whether the signals Mr. Obama is sending are intended to communicate such a message or not, they are going to be read by Israel's enemies as evidence of a profound rift between the United States and the Jewish State.
It is such an elementary, yet profound, decision to make as a new year begins: to choose to be a first responder in the broadest sense of that phrase.
The writer-director George Nolfi, by literalizing and supercharging what Dick sketched out, and adding gimcrack history and theology, has made a strenuously silly digital-action film, interrupted by a wheezing discourse about freedom and choice and other such profound matters.
The sooner the supporters of Senator Cruz recognize the profound difference between opposing a political appointment or opponent and smearing such an individual through lies and innuendo, in the tradition of Joseph McCarthy, the sooner we can put the breaks on Senator Cruz and his misguided desire to repeat the serious and harmful errors in our past.
In recent years, a number of fields have begun to wrestle with this problem, but none with such profound social consequences as the profession of teaching.
Downs had been, though, no one had a more profound impact on Robinson's life than Branch Rickey, whose religious devotion was such that he didn't attend baseball games on Sundays.
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What was remarkable however, was the level of contempt combined with profound lack of judgment in allowing a virtually unknown reporter with whom they had no sustained relationship to such unfettered access.
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