The Convention stipulates that degrees and periods of study must be recognised unless substantial differences can be proved by the institution that is charged with recognition.
All generalizations based on gender ignore substantial differences arising from culture, upbringing, education and the hundreds of other factors that make the individual unique.
But as prolific as the NFL has become in its ability to divert eyeballs to televisions, there are substantial differences in the relative popularity of its 32 teams.
But that 9% average hid substantial differences between divisions.
Ability to execute: What may be the case, is that despite doing pretty much the same thing, following the same strategy, there can be substantial differences between the firms in terms of their profitability.
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Virtually all measures of academic achievement have shown substantial differences in the performance of African-American and white students in the United States, and these performance differentials have been a source of constant analysis and discussion.
But given these honest and substantial differences between the parties about the need to regulate the insurance industry and the need to help millions of middle-class families get insurance, I don't see how another year of negotiations would help.
There were also substantial differences in the rate of change among 11 states that completed the survey in both 2006 and 2008, ranging from a decrease of 20% in Alabama to an 80% increase in Florida, according to the report.
But there are substantial regional differences in the availability of places - with surpluses in some areas, but an acute pressure on places elsewhere.
But are you actually seeing a substantial narrowing of the differences already before the President sits down with these folks?
Already there are substantial state-to-state differences in what nurses are allowed to do without the supervision of doctors, differences that tend to reflect the entrenched political power of doctors rather than any sound public policy research.
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