Pneumococcal disease is a substantial cause of illness and death.
The group said it would cause substantial harm to the architectural qualities of the building.
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Volatility is here to stay, all three experts agree, because a simple weather event can cause substantial damage.
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It was unconvinced that the structure on the side of the Geffrye Museum would not cause substantial harm to the Grade I Listed Building.
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Today violations of the personal trading rules by portfolio managers, such as front-running, which cause substantial monetary harm to investors, are still not required to be shown to investors.
The call for greater transparency of regulation is given weight by a suggestion that information on the utilities held by regulators should be disclosable unless companies can show that this will cause substantial harm.
Uncertainty over the situation in Saudi Arabia has rattled markets in recent weeks, as fears that social unrest could spread to the oil-rich kingdom could cause substantial supply disruptions and derail the global economic recovery.
The records from a particularly warm period called Marine Isotopic Stage 11, which occurred around 400, 000 years ago, suggest that warming of 1.5C compared to the present is enough to cause substantial thawing of permafrost - even in areas far north from its present-day southern limit.
These factors have combined to cause a substantial dip in thermal coal shipments as well as realizations.
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By inhibiting SGLT2, the drugs cause a substantial increase in the amount of glucose that flows out in the urine.
The choices are now what they ever were: an American or an Israeli strike, which would probably cause a substantial war, or living in a world with Iranian nuclear weapons, which may also result in war, perhaps nuclear, over a longer period of time.
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The childhood vaccine for whooping cough has not been raised as a possible cause of autism, and the vaccines that were concerning have been shown not to cause autism with substantial evidence, said Stacey Martin, a staff epidemiologist at the U.S. Centers for Disease Control and Prevention who works on pertussis.
It will probably take a more egregious departure from its roots than Michelle Rhee to cause Change.org substantial harm.
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This press release contains "forward-looking statements" (within the meaning of the Private Securities Litigation Reform Act of 1995), which are based on current expectations and assumptions about Corning's financial results and business operations, that involve substantial risks and uncertainties that could cause actual results to differ materially.
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Any broad based action would cause an immediate and very substantial dislocation in the markets.
Only a modest handful of substantial donors truly have risen to the cause of human dignity.
And I guess it could be substantial down there, if they wanted to cause problems for us and exert their influence down there.
' Were these voices to carry the day, the negative effect on progress towards gender equality would be substantial, but crucially it would also undermine the cause of reducing 'inequality.
In its report, the CBO said it expected the US recovery "to continue at a modest pace" for the rest of 2012 but warned that "substantial changes to tax and spending policies" would cause the US to tip back into recession next year.
Once again, substantial gains among lowest achievers generally was seen as the cause of the overall gains.
They point out that recent economic reports show the economic recovery has gotten itself back on track, is not in the danger of a double-dip the Fed saw a couple of months ago, that substantial further quantitative easing is not needed, and will cause more problems than it solves (including further angering nations around the world, and creating a currency war).
The argument put forward is that there are things other than climate change which might cause the entire breakdown (or less emotionally, substantial and unpredictable change in) the environment and ecosphere that supports us all.
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