Despite Suarez sealing the three points with a stunning second-half strike from a tight angle, the crucial breakthrough that infuriated Bruce so much was the spot-kick awarded 11 minutes before the interval.

BBC: 'Bizarre' penalty angers Sunderland boss Steve Bruce

Then they invariably overlook the strengths of also-ran firms, which field large sales forces and often buy or strike alliances with biotech and other drug outfits that lack marketing muscle but create potential breakthrough products.

FORBES: Drugs of Choice

Public sector trade unions have already said they will go ahead with ballots for mass strike action on 30 November over pensions, after talks with ministers failed to reach a breakthrough.

BBC: Pensions: Local Government Group reveals new plan