The North West Regional College delivers courses at nine locations throughout Strabane, Limavady and Londonderry.
Co-operative Travel shops in Strabane, Coleraine, Limavady, Newtownbreda, Antrim and Bangor are also set to shut.
The North West Regional College employs 852 staff at its campuses in Londonderry, Limavady and Strabane.
The high street retailer employs 50 staff in Londonderry and a further 30 in Strabane.
Rectory Field and William Street in Londonderry, Greenfield in Strabane and Thackeray Place in Limavady may shut.
Belfast, at 8.1%, has a higher rate of unemployment than the traditional jobs black spot of Strabane, 7.6%.
Ryan Dolan from Strabane, County Tyrone, has been announced as Ireland's entry for the 2013 Eurovision Song Contest.
BBC: Strabane man Ryan Dolan secures Eurovision place in Sweden
More than 100 children have travelled to other schools in Strabane and Castlederg since the blaze on 1 September.
BBC: Arvalee Special School in Omagh set to reopen after fire
Pupils were sent to other schools after the fire, some in Castlederg and Strabane, adding hours to their journeys each day.
BBC: Arvalee Special School in Omagh set to reopen after fire
These will run from Londonderry, Enniskillen, Omagh, Strabane, Dungannon, Cookstown and Magherafelt.
The boy, thought to be 14, got into difficulties at Moy Road, Cullion, between Derry and Strabane, at about 20:00 BST on Tuesday.
Schools and communities in Belfast, Armagh, Coleraine, Strabane, Newry and Portadown will also receive new sports facilities, changing rooms and outdoor play areas.
BBC: NEWS | UK | Northern Ireland | Lottery cash for island sports
The police said 1, 000 bangers, 125 rockets and two boxes of fireworks were found during the search of a house at Evish Grove, Strabane, on Saturday.
BBC: NEWS | UK | Northern Ireland | Damage surges over Halloween
It was unable to open for the new term and for the past four weeks its pupils have been travelling to other schools in Castlederg and Strabane.
The list of those towns with the shortest life expectancy is dominated by places in Scotland and Northern Ireland, such as Castlederg, Strabane, Belfast, Saltcoats, Londonderry and Prestonpans.
Strabane District Council Chairman Thomas Kerrigan of the DUP said his town was a great place to live, and getting better with more housing and plenty of activities for locals.
BBC: Strabane in County Tyrone has a population of about 15,000
Two of the leading Scottish planters, the Earl of Abercorn and his brother, Sir George Hamilton, were Catholics themselves and settled their lands in Strabane almost entirely with Scottish Catholic families.
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