So, diagnosis, design and implementation of solutions should start from this reality.
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Beyrer makes clear from the start that this is a personal account from a survivor who has worked on the AIDS front-line for over a decade.
And it may not be long before these two industries start to suffer from this one small innovation with dramatic repercussions.
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"There was never any doubt in my mind from the start that this match would go ahead, " he said.
So it was pretty clear from the start that this was going to be resolved by the Algerians only.
It was clear from the start that this bridge is much more than an expedient path between points A and B.
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It was determined from the start that this would be an interim role, and that we would search for my replacement.
And the parameters of that discussion, whose start has been deferred from this year to next, have yet to be set.
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From the start of this bitter 1951 film noir, directed by Joseph Losey, the forces of order are as much a menace as a comfort.
From the start, this meltdown has reflected a crisis of confidence.
Now, from the start of this campaign, I've identified this as one of my top priorities and here is what I think we have to do.
The South Africans won the first Test 26-21 in Durban last weekend after holding off a late fightback by the Lions, but were on the back foot from the start this time around.
How will James react, if he finally collects the one goal that has eluded him, that has hovered over his head from the start of this contentious Miami experiment no, check that, since he entered the league, a pre-lionized high schooler?
From the start of this Super Bowl XLVII season, Mercedes-Benz has embraced an association with the Big Easy that began in earnest with a naming-rights deal that led to the placing of its iconic star emblem all over the Superdome in 2011 in full knowledge that the 2013 Super Bowl would be played there.
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The government hopes to reverse this trend when millions of lower paid employees start to be automatically enrolled, from later this year, into either existing company schemes, or into alternatives such as the new national employment savings trust (Nest).
Almost by definition, this will start from a new, smaller base, but it needs to start.
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Bhatia hopes to start acquiring land from local farmers this fall and to have all of the land in his possession by next March.
And the Americans, having first demanded that the North abandon its nuclear programmes before any talks could start, are sliding away from this stance.
With less than 48 hours from start to finish, this marks the shortest period of time it has taken to plan and complete a spacewalk mission.
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Now, the chart doesn't contain a ton of additional information that would help put it in context -- a specific time period in 2007 would be nice, as would and driver and OS versions -- but we've been hearing about NVIDIA issues with Vista from the start, and this seems to confirm it.
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Germany has been against this simple but certain path from the start but it seems about to open the gates to this hard road at the end of the month, when Europe must state its solution to the imminent unraveling of the EU financial system or perish.
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This transfer will start from April 1, is expected to be completed by the end of September.
He built his campaign on a fundamental belief that change in this country must start from the ground up, not the top down.
My observation is that start-ups can benefit from using this framework.
But the question moving forward is whether Facebook will have learned from this experience and start to manage its hype and greed to protect its brand.
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"This was a great victory for us...we planned for this, executed these plans perfectly and controlled this game from start to finish, " Langer told the Somerset website.
BBC: SPORT | Cricket | Counties | Somerset victory seals promotion
There will, at least, be no repeat of the scheduling that led to Scotland playing Norway away from home at the start of this season, resulting in a 4-0 defeat.
As I said from the start, we understood that this could be really bad.
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You have to hand it to Ms. Wheeler who had this nailed from the start.
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