Blue Gene could simulate heating a protein, to see how stable it is, or could apply random mutations to a protein, to see how its ability to fold is affected.

ECONOMIST: REPORT: COMPUTING: Big Blue��s big bet | The

The researchers were able to form three types of mutants in the protein, in which one or both of the alpha helices were made more stable than they normally would have been.

ECONOMIST: Folding stuff

David Schenkein , head of clinical oncology at Millennium, says 85% of these patients are now stable or better, and 11% of them had a 90% reduction in their tumor protein levels after only some treatment.

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