Karthik reached his half-century in fine style by driving James Kirtley for four, and twice dispatched him off the back foot to the square cover boundary.
The resumption lasted only 13 balls, but in that time Lumb produced a great catch, sprinting 20 yards along the square leg boundary before diving full stretch to take Paul Stirling's pull shot.
Overnight partner James Hildreth was run out by Richard Grant's direct hit at the non-striker's end for 69, and Mckenzie's own innings came to an end when he was caught by Andrew Davies off Croft on the square leg boundary as he looked for a 13th four.
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Lusty late blows from Mike Hussey - including a huge six into the third row of the top tier of the square leg boundary - bumped up the total, but the left-hander fell one run short of his half century when he drove a catch to Denly at mid-off.
In a tense finish, Amla kept his cool despite the loss of Chris Read, Franks and Broad, hitting Willoughby for 18 in one over, and ending the match with a pull to the square leg boundary to finish unbeaten on 64 from 73 balls with nine fours and a six.
Last man out Kwebiha was then caught by Moneeb Iqbal off Stander on the square-leg boundary leaving Asadu Seiga not out on eight.
On 59 he hooked Siddle to the square-leg boundary, Shane Watson took the catch but realising he was heading over the rope he parried the ball upwards but could not prevent it going for six.
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Franklin pulled Richardson to the square-leg boundary where he was caught two-handed low down by Alexei Kervezee before Taylor, top scorer in Gloucestershire's first innings with 71, swung across the line against a delivery which kept low.
Shoaib returned for another burst but could not find the same speed with the older ball and was not as dangerous, Ganguly with plenty of time to paddle it round past square-leg to the boundary.
He added 71 for the fourth wicket with Neil Broom (24) but the pair departed in quick succession, with Taylor clearly angry with himself after pulling a short ball from Shane Watson straight to the boundary fielder at square leg.
Majid Haq struck the opening boundary with an elegant square drive in the ninth over, with Watson cutting to the fence in the next during an encouraging spell for the Scots.
As soon as Karthik square cut James Anderson to the boundary in the first over from the Radcliffe Road End it was clear there was unlikely to be a serious challenge to India's victory parade.
After a 105-minute delay, another hour was possible, in which Pietersen passed 50 for the seventh time in just his 10th Test, square-driving Pathan for his ninth boundary.
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