Guardiola won La Liga, the Spanish Cup and the European Champions League in his first season as Barca manager in 2008-09.
He has also guided Real to a Spanish Cup win, while his team will play city rivals Atletico in this year's final.
Both Spanish Cup and European ties are finely balanced at 1-1.
In his final season Barca only managed to win the Spanish Cup before Guardiola stunned world football by saying he needed time away from the game.
Real's former Chelsea coach Jose Mourinho celebrated his second Clasico victory in 11 clashes, and first in the league, having won the Spanish Cup last year.
CNN: Clasico win gives Real the title edge as Barca lose again
Last month he described this season as the worst in his career after losing the Spanish Cup final to Atletico Madrid, meaning no trophy for Real in 2012-13.
Eto'o was part of the Barcelona team that won last season's unprecedented treble of Champions League, Spanish league and Spanish Cup and scored more than 100 goals for the Catalan club.
Toure feels Barcelona are starting to feel the strain of playing fast-paced football with trying to clinch a third European Cup, win the Spanish league and the Spanish Cup (Copa del Rey).
"We're very happy to get 55 out of 57 points, but logically it will be difficult to repeat that with the Champions League and the Spanish Cup to think about as well, " Vilanova told reporters.
While Real have been off the pace in the Spanish league this season -- Jose Mourinho's side are 12 points behind Barca -- the Madrid club beat their Catalan rivals recently in the Spanish Cup semifinals.
CNN: Spanish giants kept apart in Champions League semifinals
Despite a recent draw against Barcelona at the Nou Camp, Valverde has paid the price for an inconsistent season which has also seen the club crash out of the Spanish Cup to second division side Celta Vigo.
He presided over an unprecedented treble in his first season in charge, winning the Champions League, La Liga and the Spanish Cup, having been promoted from his role as coach of the Barcelona reserve side in May 2008.
"Fulham have excellent players, " said Flores, who has also guided his side to a Spanish Cup final against Sevilla since taking over from Abel Resino, who departed in the wake of the club's 4-0 Champions League drubbing at Chelsea last October.
Barca, eight points clear at the top of La Liga and due to face Real in the Spanish Cup final on Wednesday 20 April, are bidding for a repeat of the Treble they achieved in coach Pep Guardiola's first season two years ago.
Iker Casillas retained his place in goal, having been handed a second chance alter an injury to his replacement Adan, but Mourinho would not guarantee that the Spain captain would stay in the team for Tuesday's Spanish Cup quarterfinal first leg against Valencia.
As Barca coach, Guardiola presided over an unprecedented treble in his first season in charge, winning the European Champions League, La Liga and the Spanish Cup, having been promoted from his role as coach of the Catalan club's reserve side in May 2008.
That would set up the mouth-watering prospect of four El Clasicos in the space of little more than two weeks, with the clubs also due to meet in La Liga on Saturday 16 April and in the Spanish Cup final on Wednesday 20 April.
The young Fabregas continued to live at home and go to school, but spent the rest of his time at La Masia, training, eating and studying at the famous institution which produced seven of the Barcelona side that won the treble of La Liga, Spanish Cup and Champions League in 2009.
Van der Sar saved well from Puyol as Barcelona dominated until the final whistle - and not even the most partisan Manchester United follower can doubt that Pep Guardiola deserved to round off a dream first season in charge by adding the Champions League to the La Liga title and the Spanish Cup.
Fuentes has boasted that some of the samples he holds involve Spanish world cup winning stars.
FORBES: Soccer Hit By Doping and Corruption Revelations, All In One Day
Coach Jose Mourinho had made seven changes following last weekend's win over Rayo Vallecano, ahead of Tuesday's second leg of the Spanish Super Cup at Barca's Camp Nou.
Hewitt joined another former world No. 1 in progressing as Juan Carlos Ferrero upset seventh-seeded Spanish Davis Cup teammate Tommy Robredo 6-3 6-2 to set up a clash with German 10th seed Tommy Haas.
Despite Gil's interference, Atletico won the Spanish league and Cup double in 1996.
BBC: SPORT | Football | Other European | Atletico owner Gil dies
Toure has already held that trophy aloft, in 2009 when Barcelona completed a treble of trophies also including the Spanish league and cup crowns.
Guardiola, who has won an historic Spanish league and cup as well as the Champions League in his first season in charge, paid tribute to Lionel Messi, scorer of the second goal against United.
Ferrer has a glittering collection of winners medals, including five Spanish championships, the European Cup and an Olympic gold, but fears a cup final exit could also spell the end of his Euro 2000 dream.
"As a competitor and as a passionate players with the Ryder Cup, the Spanish have been a fantastic asset to our team over the years, starting with Seve Ballesteros, through Jose Olazabal and Miguel Angel Jimenez, " said Montgomerie.
And the President also wished the Spanish team luck in the World Cup -- which explains where Gibbs is right now, as well.
WHITEHOUSE: Press Briefing by Deputy Press Secretary Bill Burton
In addition to his grand slam triumph at Roland Garros, Ferrero was also part of the Spanish teams who won the Davis Cup in both 2000 and 2004.
Since making his Barcelona debut in 2003, he has collected three European Champions League crowns, two FIFA Club World Cup titles, five Spanish league championships and two Copa del Rey medals.
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