But I am mindful of how much farther the American space enterprise must travel to reach the final frontier of space exploration and discover the limits of our own scientific enterprise.

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Space is the final frontier and we have to make progress.

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It's not really about space, the final frontier anymore.

NPR: Space Race Permeated Pop Culture

It is true he was speaking in a state with a heavy investment in the space race, but the final frontier has been a long-standing obsession for him.

BBC: Newt's long shot at the Moon

Apparently, for billionaire adventurer Richard Branson, space is no longer the final frontier.

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Jewelry in the Space Age, an exhibition of jewelry inspired by the final frontier.

FORBES: Galleries To Launch Space-Themed Jewelry Exhibition - Forbes

The problem with writing articles about space is that you almost automatically reach for cliches, the final frontier and all that.

FORBES: The John Galts of the Future Will Build Galt's Gulch in Space

We were certain that this was just a "pie in the sky" concept, but apparently engineers are hard at work designing those futuristic space elevators that promise to eventually whisk cargo and humans to the final frontier at a fraction of the cost of rocket-based delivery systems.

ENGADGET: Space elevator robot reaches 1000 feet

The U.S. perfect it with putting a man on the man, then with a series of modern high tech space shuttle missions and Mars ROVERS. But now, the final frontier captains are more likely to be Russians, with their hopes for a human Mars landing someday, or Chinese, with a new China space station due within the next 8 years.

FORBES: China's Space Age Grows Up As U.S. Space Race Winds Down