Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.
We traced our path, following the meandering freeway through South San Francisco and into the downtown area.
Solazyme, another firm based in South San Francisco, wants to use single-celled algae to make its fuel.
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The deal announced Monday will give Elan 21 percent of the future royalties that South San Francisco, Calif.
But are investors being lulled into a sense of overconfidence in the South San Francisco biotech's ability to deliver?
The South San Francisco-based firm was the first biotech company, and it has long been considered one of the best.
Biotech Exelixis in South San Francisco took a different approach in mid-December.
But as gigantic rivals, including Pfizer and GlaxoSmithKline , try to steal its tricks, can the South San Francisco-based biotech maintain its dominance?
Similarly, Genentech, the South San Francisco-based biotech giant, held its holiday shindig at a baseball stadium, where employees skated on a temporary ice rink.
"We intend to tame fibrosis, " says Thomas Neff , chief executive of Fibrogen , a privately held biotech firm in South San Francisco, Calif.
Firms now in human trials of this approach include Dendreon of Seattle, Cell Genesys in South San Francisco, England's Onyvax and Therion Biologics near Boston.
In May, South San Francisco-based Genentech (nyse: DNA - news - people ) said that Avastin extended survival in colon cancer patients.
LS9, which is based in South San Francisco (a separate municipality that has a cluster of biotech companies), also uses bacteria to make straight-chain alkanes.
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Genentech, the big biotech firm in South San Francisco, hired him in the late 1980s for his expertise in how fish absorb fat through their intestines.
Recruiters often reached out to George Scangos, a confident, analytical type who three years ago was running a small biotech company in South San Francisco.
South San Francisco resident Vindy Chiu signed up her 6-year-old dog, Turbo, for swimming classes because she feared the white Eskipoo had inherited her apprehensions about water.
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Pfizer's acquisition of Rinat Neuroscience of South San Francisco, announced last month, takes the world's largest pharma company a step further into the world of biologics as well.
Lieberburg has been developing Alzheimer's medicines at Elan's South San Francisco research labs for a decade and a half, since they were a standalone biotech called Athena Neurosciences .
The biggest corporate presence will be Genentech (nyse: DNA - news - people ), the South San Francisco biotech that has built itself into a cancer-fighting giant.
But today's news is especially auspicious, because the South San Francisco-based firm is developing Avastin entirely by itself--meaning the company wouldn't have to share sales or profits for the drug.
Both analysts, however, agree on one thing: They both rate shares in South San Francisco-based Genentech "outperform, " even though the stock traded at a whopping 53 times Chao's 2005 earnings-per-share forecast.
Solazyme, founded in 2003 and headquartered in South San Francisco, uses patented technology that allows algae to produce oil and biomaterials in standard fermentation facilities quickly, efficiently and on a large scale.
In the past 18 months JPMorgan Partners has surveyed 300 nano business plans and invested in only one: Optiva, a South San Francisco firm that wants to use nanotech to make thin-panel displays.
Tularik announced after Monday's close that the U.S. Food and Drug Administration has green-lighted the design of what could be the final clinical tests for the South San Francisco-based biotech's liver cancer drug, T67.
Similarly, Genentech (nyse: DNA - news - people ), the South San Francisco-based biotech giant, held its holiday shindig at a baseball stadium, where employees skated on a temporary ice rink.
California, the birthplace of biotech and home to granddaddy Genentech in South San Francisco and Southern California big shot Amgen, made it onto FierceBiotech's hot spot list because of the California Institute for Regenerative Medicine.
Genentech (nyse: DNA - news - people ), the big biotech firm in South San Francisco, hired him in the late 1980s for his expertise in how fish absorb fat through their intestines.
Pfizer's (nyse: PFE - news - people ) acquisition of Rinat Neuroscience of South San Francisco, announced last month, takes the world's largest pharma company a step further into the world of biologics as well.
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