• The big bottleneck in going from gene to drug is having the chemical know-how to create a small molecule drug, the kind of chemical that can be produced very cheaply and sold for a lot of money.

    FORBES: Magazine Article

  • The 657-employee company is developing a small-molecule drug to fight advanced solid tumors, metastatic brain tumors and blood cancers, as well as refractory, ovarian and prostate cancers.

    FORBES: Magazine Article

  • For small molecule drugs, the lifeblood of drug companies like Pfizer and Merck, it is one in 25.

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  • Second, large drug companies are trying to avoid traditional small molecule drugs that will face large generic uptake after their patents expire.

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  • It is in the process of completing the acquisition of Allos Therapeutics (ALTH), whose drug, Folotyn, is a small-molecule therapeutic for cancer.

    FORBES: Why This Tiny But Profitable Biotech May Be Gobbled Up By Big Pharma

  • Because most small-molecule drugs can be manufactured with easily replicable chemical processes that lead to a largely reproducible drug formulation, the clinical trial data that supported approval of the original version can be relied upon for the generic versions.

    FORBES: Commentary

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