The group found that patients with small cell lung cancer did have signs of the antibodies.
There are two other non-small cell lung cancer trials of Nexavar listed on clinicaltrials.gov.
He explained that she had a non-small cell lung cancer that had started in her left lung.
Pharmion has a treatment for small cell lung cancer that is about to enter a late-stage clinical trial.
Recentin, for non-small cell lung cancer and colon cancer, will go to the FDA in 2009 or later.
Down the road, it could also gain approval for pancreatic, head and neck, and non-small cell lung cancer.
Zactima, for non-small cell lung cancer, should be filed with the Food and Drug Administration toward the end of next year.
One is crizotinib, for 5% of patients with non-small cell lung cancer.
Vandetanib, the drug approved today, failed in non-small cell lung cancer and in bladder cancer before it proved effective in medullary thyroid cancer.
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When Margaret Edwards was diagnosed with small cell lung cancer last September she was devastated to be told it was too late to operate.
In trials unveiled in May, Iressa shrank tumors in 10% or more of patients with non-small cell lung cancer who had failed other chemotherapies.
The first data on Iressa were promising: It seemed to help patients with non-small cell lung cancer when it was given on its own.
Tarceva has already produced promising results in a trial on patients with non-small cell lung cancer who had already been heavily treated with chemotherapy.
The world's first patient trial is using a drug combination of Thalidomide and chemotherapy to treat small cell lung cancer, the most deadly form of lung cancer.
In a study conducted with many patients in Japan, 28% of non-small cell lung cancer patients saw their tumors shrink with Iressa, compared with 10% of Caucasians.
The Genentech drug has slowed down colon tumors, non-small cell lung tumors and now breast tumors, and has opened up more areas for development of future medicines.
In an in vivo model using severe combined immunodeficient mice, subcutaneous tumors were generated by inoculating the animals with cells from human non-small cell lung carcinoma cell lines.
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Most notably, we completed U.S. and Japanese filings for crizotinib in ALK-positive non-small cell lung cancer and U.S. and EU filings for axitinib in advanced renal cell carcinoma.
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Results in non-small cell lung cancer show that Abraxane does shrink tumors 31% better than Taxol, which the company says should be enough for an FDA approval in that disease.
All of the doctors set a similar hurdle: If more than 5% of patients suffered life-threatening bleeding, it would be difficult to prescribe Avastin widely for non-small cell lung cancer.
It wasn't until Tarceva extended the lives of patients with non-small cell lung cancer that it became clear that OSI and Genentech actually did have a potential blockbuster on their hands.
The study, of patients with non-small cell lung cancer who were also receiving chemotherapy, showed an increase in "local failure, " meaning cancer cells at the radiation site either weren't killed or began growing.
Do Bayer and Onyx have the option of modifying these studies so that they might, given this new information, stand a better chance of proving a benefit for Nexavar in non-small cell lung cancer?
Among the bargain stocks, Berry says, is Cell Genesys (nasdaq: CEGE - news - people ), which has a number of products in late stage-three trials, including a vaccine for non-small cell lung cancer.
It seems to be particularly important for the growth and survival of some cancer cells and large amounts of the molecule are often present in the cells of non-small cell lung cancers, sometimes in a mutated, over-active form.
Separately, Pfizer said that the Food and Drug Administration has approved Xalkori capsules, which the company calls the first-ever drug targeting anaplastic lymphoma kinase, or ALK, for the treatment of locally advanced or metastatic non-small cell lung cancer that is ALK-positive.
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In non-small cell lung cancer, for instance, the tissue samples needed to identify these genetic markers are not routinely taken for practical reasons, says Mark Kris , an oncologist at Memorial Sloan-Kettering Hospital in New York who has worked with Iressa and with OSI's Tarceva.
Bayer and biotech Onyx Pharmaceuticals announced a devastatingly disappointing result for their cancer pill Nexavar: They stopped a study of the drug in non-small cell lung cancer early because there was no chance it would reach its main goal of proving Nexavar extends patients' lives in that disease.
The drug did seem to help non-small-cell lung cancer patients live slightly longer compared with a control group.
Additional studies will evaluate the effectiveness of the pill in glioblastoma, a lethal brain tumor, small-cell lung cancer and prostate cancer.
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