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It was also once thought to cure toothache and be a sleep aid if taken as a cup of tea.
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Among them is Pfizer, which handed the agency the ad assignment for its much-anticipated sleep aid Indiplon, due out later this year.
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For all the names, the main ingredients are the same: Vitamin B6 plus the over-the-counter antihistamine doxylamine, found in the sleep aid Unisom.
NPR: FDA Approves Return Of Drug For Morning Sickness
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For reference, Schedule IV drugs include anti-anxiety benzodiazepines such as lorazepam (Ativan), the sleep aid zolpidem (Ambien), and another older weight loss drug, phentermine (Adipex).
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In 2007, the sleep aid Ambien from Sanofi-Aventis joined that group.
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AEG's attorney says the case is about personal choice, namely Jackson's decision to have Murray serve as his doctor and give him doses of a powerful anesthetic as a sleep aid.
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"There really isn't any compelling scientific evidence to use valerian as a sleep aid, " says Meir Kryger, a professor of medicine at Yale University School of Medicine in New Haven, Conn.
WSJ: Can a Root Get to the Problem of Insomnia?
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Your favorite travel sleep aid?
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No Rozerum tab sleep-aid necessary.
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And, at low doses, Zyprexa and AstraZeneca's Seroquel are often given as a sleep or calming aid.
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The promise is that, with the aid of a special algorithm, the band will help you sleep better, wake up happier and nap more effectively.
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Frazer Robson, of Shelter Housing Aid and Research Project (SHARP), said the proposed cuts could force more people to sleep rough on the streets.
BBC: Petition opposes Leicester City Council homeless cuts