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Wendy Slaney announced she was leaving her post at the James Paget Hospital (JPH) with "real regret".
BBC: Wendy Slaney
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Edward Slaney, 35, was crushed by a lorry that was blown over near Bridgewater Place in March 2011.
BBC: Action plea after wind death near Leeds high-rise
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Strong winds at Bridgewater Place led to a lorry being blown over in 2011, killing pedestrian Edward Slaney.
BBC: Bridgewater Place
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Edward Slaney, 35, of Sowerby Bridge, West Yorkshire, was crushed after strong winds toppled a lorry near Bridgewater Place in 2011.
BBC: Bridgewater Place 'wind tunnel caused Leeds injuries'
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Indeed when Zola Budd notoriously tripped Mary Decker-Slaney in the Los Angeles Olympics there was never any question of running the race again.
BBC: Curtain comes down on Paralympics
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Mrs Slaney, who has held the position at the Gorleston since March 2010, after being interim chief for 12 months, said she had thought "long and hard about the best way forward".
BBC: Wendy Slaney