Those will take years, and a single serious side effect could sink the drug.
We have a five year track record with not a single negative side effect and the vast majority of people having benefited.
It was also a single paper finding this effect, which may not be found by other researchers.
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"Pesticides are the single worst negative side effect of lawn care, " Milesi says.
The total effect of a single room and certainly of a whole visit could be both confusing and exhilarating.
But the extraordinary effect of a single bureaucratic bungle has been to knock 0.6 percentage points off Japan's growth.
However, a few hundred peacekeepers in a single province will have little effect.
The investment vehicle being created by Goldman is intended to pool investors' money to create the legal effect of a single new shareholder in Facebook, since each special-purpose vehicle counts as one shareholder of record.
The investment vehicle being created by Goldman is intended solely to pool investors' money to create the legal effect of a single new shareholder in Facebook, since each special-purpose vehicle counts as one shareholder of record.
"Through the Tunnel" is an accomplished fable about a young boy's initiation in Mediterranean waters, while "The Day Stalin Died" follows the pathos and comedy of a London writer and "To Room Nineteen" examines the effect of a single act of infidelity on a supposedly sturdy British marriage.
So if cable wins the fight, there will, in effect, be a single gatekeeper controlling most people's access to the Internet.
So is the aging of the population, creating more single widows and widowers, an effect that will grow as the baby boom retires.
The author says that no single innovation will have a more profound effect than the conversion of biological data.
Similarly in 1992 the U.S. National Academy of Sciences (NAS) put forward the idea of launching 55, 000 "solar sails" into orbit around the Earth, each with an area of 100 square kilometers, the sails collectively producing the same effect as Early's single glass panel.
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But there are only a few cases where we know the relationship of a specific mutation to a specific effect, and also only a small number of cases where an effect is determined by a single gene rather than the combined effects of hundreds or thousands of genes.
He added that the GOP prefers having the reductions take effect instead of having "a single tax loophole" disappear for those who don't need it.
One could argue that the actions of any single small business may not have a big effect on the country or the economy, but how small-business owners or managers make decisions about employees can and will affect a great many lives.
However, the scenarios included multiple rounds of negotiation, so there was room for give-and-take: in a third experiment, with negotiation focused on a single issue, mimicry failed to have its desired effect.
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Also controversial was the suggestion that there would be a multiplayer mode, and that this multiplayer would have an impact on the single-player story which had so far defined Mass Effect.
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This problem is compounded by the possible presence of multiple chemicals which together have an additive effect that greatly increases the lethal action of any single chemical.
Concentration is improved when people's senses are aroused, says Dr Linnell, but if this becomes excessive it seems to have the opposite effect and reduces the ability to focus on a single task.
"The possibility that current climate models underestimate the effect of solar variations on climate is probably the single most contentious issue in climate research at the moment, " said Dr Myles Allen of the department of physics at Oxford University.
The changing income pattern is not reflecting economic effects, but the effect of the demographic change of more lower income earning single households replacing higher income earning married households.
True, Mass Effect 3 had multiplayer components, but it remains primarily a single-player experience.
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This announcement has no impact on the single shifting actions or separation programme that was announced in February to take effect at shut down this year.
In his view, the uncanny valley effect has to do with a mismatch in features of a single animation or robot, with some parts appearing much more humanlike than others.
Every single dish had a subtle decorative motif from its essential ingredients that complemented the overall effect without being in any way redundant.
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In fact, the lack of a single market in money is a serious blockage in the economy that can have a direct effect on companies.
Further, implementing multiplayer in single player games forces comprimises in gameplay and budgets, as we saw clearly demonstrated with Mass Effect 3.
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