Gelb pointed to the shift in Congress as the single biggest factor at work.
Concern about neglect is the single biggest reason for people contacting the NSPCC helpline.
"Positive attitude is the single biggest thing that can change a business, " says Johnston.
And it has been the single biggest drag on our recovery from a terrible recession.
Holding cash, Miller says, was the single biggest detractor to his performance in 2012.
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For advertisers, the Super Bowl is now the single biggest marketing event of the year.
Since then, our floating, unstable dollar has been the single biggest impediment to robust economic growth.
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The single biggest predictor of poverty among women is the birth of their first child.
The U.S. visa system is the single biggest obstacle in attracting more international tourists.
It bears stating: This is the single biggest sporting event in the state's history.
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Officials say that the project has the potential to be Afghanistan's single biggest foreign investment project.
"It would be the single biggest-day pharma stock move I'd ever seen, " Dr. Schoenebaum said.
Mr. GIULIANI: Fred was the single biggest obstacle to tort reform in the United States Senate.
But, to do that, the single biggest thing we need is to move faster.
That's the single biggest problem for most airlines, is fuel costs that skyrocket or are unpredictable.
The commission considers the inability to speak English to be the single biggest barrier to integration.
The housing crisis has been the single biggest drag on our recovery from the recession.
Unemployment remains the single biggest blot on the economic landscape: it still runs at 10.5%.
Thirty-nine percent said job-hopping was the single biggest obstacle for an unemployed job seeker.
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One thing we all have in common is, regardless of income-level, Americans' single biggest expense is housing.
My single biggest personal improvement as CEO occurred on the day when I stopped being too positive.
"Dynex came through last year the single biggest contraction in semiconductor history, " says chief executive Michael LeGoff.
Without question, Kennedy has been the single biggest legislative champion of health care reform since the 1960s.
But the single biggest reason for a long, tortured negotiation is not so obvious to most of us.
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It also reinforced that the single biggest thing that predicted my future success or failure was mental strength.
It is the single biggest question occupying Labour MPs thoughts and many had been expecting some clearer hints.
So, again, that would -- that is the single biggest component that makes up the so-called fiscal cliff.
Hamm started leasing land in 2003 and is now the single biggest holder, with the rights to 900, 000 acres.
That stability was probably the single biggest benefit of the past three years.
Coronary heart disease (CHD) is still the single biggest killer in the UK, claiming nearly 125, 000 lives a year.
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