Antigens stick out from cells like molecular signposts, saying kick me to the immune systems soldiers.
And investors may look to ideas like Google Glass as positives signposts for long-term investing.
For all the historical signposts though, there are reasons to expect England to prosper in Perth.
And signposts are exactly what companies want as they plan campaigns down to the most minute detail.
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To restore confidence you have to establish signposts that the world after the crisis will be different.
Signposts provides support to people in Morecambe, Lancaster and Preston with issues such as unemployment, homelessness and poverty.
The breakthrough, described in the journal Science, is based on 150 genetic "signposts" found in exceptionally long-lived people.
That may be good enough for mapping key signposts on chromosomes, says Venter, who recently joined the company's board.
Drive through the lush countryside and follow the signposts to each locale, which can be visited in any order.
It will be a demanding road for the young Breaker participants, but at least one with plenty of signposts.
Hurricanes long since graduated from being singular weather events to becoming climatic signposts.
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Those metrics, added to what we had in 2011, give us signposts by which we can judge our progress.
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There are signposts everywhere to make sure that tourists do not end up as lunch, but very occasionally they do.
But we need some daily signposts that we are not novel, not better, not worse from those who came before us.
Supply-chain managers also should mine their in-house data thoroughly for signposts as to how they can strengthen relationships with key suppliers.
My first ever speech to you - 11 years and 22 conference speeches ago - was about signposts for the way ahead.
The Boston team created a mathematical model, which takes information from these signposts to work out a person's chance of reaching 100.
And, as usual, investors are looking for signposts manufactured from earnings reports that might give them a heads-up on the direction of the whole market.
Tony Benn said of her that politicians were divided between weather vanes and signposts and that Margaret Thatcher was a signpost and he respected that.
Signposts will cease operation on 26 April and it is hoped volunteers and members of staff can be moved into other organisations and community projects.
"These results are like signposts on the long-term strategic road, building confidence and encouraging us to continue moving forward together, " says Treasury Secretary Henry Paulson.
With its tree-lined dirt roads, whitewashed cottages and vintage signposts giving distances in miles (South Africa converted to metric in the 1970s), Nieu Bethesda is an off-the-grid destination.
But we would prefer to work with better signposts and guidelines.
Traders in Masham say they suffered a 30% drop in visitor numbers after signposts on the A1 were removed when the road was widened in 2009.
That may be good enough for mapping key signposts on chromosomes or rapidly locating a few key gene variations, says Venter, who recently joined the company's board.
More positively, community councils can help play a part in instilling civic pride by organising local events and festivals - even little things such as signposts highlighting interesting local buildings.
As such, they are signposts along the genome that provide clues to what version of a gene a person may have, and whether it's been linked to some particular disease.
Meanwhile, he held tight to the wheel and adhered to the speed limit, because he wanted nothing to interfere with his momentum, no rules to be broken, no winking signposts missed.
The fragments served as signposts for Richard Preston, the best-selling author of the nonfiction book "The Hot Zone, " who was brought in by the Michael Crichton Trust to finish the partially written manuscript.
Several people familiar with the deal told the Financial Times that the US internet giant will revamp its results page to include prominent links to rival search engines and clearer signposts for its own in-house services.
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