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Abdominal pain and diarrhea are common but not universal, and some people suffer from significant weight loss.
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The second paper also failed to find statistically significant weight loss in a similar study on teens, except for one subgroup.
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That drug, rimonabant, produced significant weight loss and a drop in fasting insulin levels by affecting certain cannabinoid receptors in the exact opposite way that THC, marijuana's main psychoactive ingredient, does.
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After the 2004 surgery, Mr. Jobs and his company said little about his health until January 2009, when his significant weight loss and a decision to forgo his customary appearance at a major trade show raised new concerns.
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At the time the FDA said the drug resulted in "significant" weight loss but the agency said it was concerned about a possible risk of birth defects and an unknown impact on the heart.
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They show that significant physical activity can help with weight loss, and that it has the added bonus of making you healthier in general.
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Secondly, losing weight too quickly when you don't have a significant amount of weight to lose can result in muscle loss as well as fat loss, which can decrease your metabolism and make it more difficult to maintain your weight loss.
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While many diets can induce short-term weight loss, dieters often regain a significant portion within a year, in part because dieting tends to increase sensations of hunger.
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The weight loss results were not impressive, but were statistically significant and strengthen the case for the drug, which the FDA rejected last month.
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