In chess how significant of an advantage is playing white in grandmaster level games?
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One of the most strategically significant of these proposed actions would involve extremely accurate machine tools.
This is surely the most significant of the elements that Tolkien brought to fantasy.
It could well turn out to be the most significant speech of Labour's pre election campaign, and certainly the most significant of Gordon Brown's political career.
The most significant of these is that all over the globe, people show by their actions and their choices that they cherish the opportunity to drive.
"Pursuing perfect babies, ageless bodies and happy souls with the aid of cloning, genetic engineering and psychopharmacology, " he thinks, are among the most significant of those threats.
For the record, that's the most significant of her contributions.
The most significant of the three programs is Project 40, a partnership with Nike that plucks promising prospects out of high school and college and places them on Major League Soccer teams.
The leaked memo reportedly reflects the views of a significant number of senior and mid-level officers in Centcom, including large numbers of intelligence officers, as well as a significant number of area analysts stationed in the Middle East.
In symmetry that seems almost too perfect, much as Syria is a significant consumer of Russian weapons and hosts a Russian naval base, Bahrain is a significant consumer of American weapons and hosts an American naval base.
The satellite-borne phone will map the Earth with its 5 megapixel camera and conduct a number of scientific and engineering experiments, the most significant of which will be to hand total control of the spacecraft over to the Nexus.
By consistently providing just enough information to be confusing, HealthTap may hope to provoke a significant number of users into paying to see a participating doctor and, presumably, persuade a significant number of participating doctors into paying HealthTap for that referral.
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The other is the drama over DOMA. Being able to file a joint return is probably not the most significant of the over 1, 000 benefits that hinge on federal recognition of marriages, but it may be the one that affects the most people thereby creating the most tsoris .
So, for most of the Pashtun, the departure of the Taliban will be welcomed, but there will certainly be concerns that representatives of the Pashtun community have a significant say in the development of a new government in Afghanistan, one that reflects the significant portion of the population that is Pashtun.
This is a significant ruling by a panel made up I think of a significant mix of judges.
The Estate of Elkins has three lessons for anyone who owns or advises owners of significant collections of artwork.
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China-based auditors are also perfomring audits of significant operations of US and non-US based multinationals with US exchange listings.
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Cost considerations will probably preclude the dispersal of significant numbers of these single-warheaded missiles in a day-to-day or "alert" posture.
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The Beeching Report of 1963 ushered in an era of significant reduction of the rail network - with about a third closed.
Some pessimistic critics have begun to worry about the effective repeal of significant portions of Dodd-Frank in the months to come, if adequate funding is denied.
In fact, the Pentagon was so upset by these mischaracterizations of the B-2 program that Under Secretary of Defense Paul Kaminski felt compelled to issue a rebuttal of significant portions of the report.
But only in recent years, with the arrival of significant quantities of automatic weapons and the opening up of hitherto inaccessible forests by European and Asian companies, has the African bushmeat trade become unsustainable.
And that big possible deal includes significant reductions in discretionary spending, significant reductions in our defense budget, significant savings out of the entitlement programs, and significant savings out of our tax code.
Through the Presidential Memorandum, the President directed agencies to expedite environmental reviews and permit decisions for a selection of high priority infrastructure projects that will create a significant number of jobs, have already identified necessary funding, and where the significant steps remaining before construction are within the control and jurisdiction of the federal government and can be completed within 18 months.
They are people "with a record of significant achievement within their chosen way of life that demonstrates a range of experience, skills and competencies... who are able to make an effective and significant contribution to the work of the House of Lords".
Jam Nizamuddin Tomb is one of most significant structures of the World Heritage Site of Thatta-Makli.
In the absence of any significant discoveries of chemical or biological weapons the real reason becomes more apparent.
The collapse of a significant portion of the levee leading to the very fast flooding of the city was not envisioned.
And, a CNN-sponsored investigation revealed evidence that only one Enron executive disposed of a significant amount of stock during the lockdown.
This treatment will be, at best, highly selective so as not to offend several sources of a significant part of that danger.
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