Any significant disruption to oil production, or perceived threat of one, would likely send energy prices higher.
Access to entertainment content is driving significant disruption in new devices, platforms and business models across the globe.
FORBES: Los Angeles, Driven By Content, Is The Next Big Startup Market
"Wholesale removal of U.S. attorneys would cause significant disruption to the work of the Department of Justice, " he wrote.
However, customers have been advised to prepare for "significant disruption", the company added.
The agency is warning motorists to expect significant disruption during resurfacing work planned for February and June 2013.
But inspectors said changes to the drug treatment system had been "badly introduced" and caused "significant disruption" at the prison.
The blaze - the cause is not yet known - is expected to cause "significant disruption" to services in mid-Cornwall, including school buses.
If you follow the trends over the last few years and project them out, it sets the stage for yet more significant disruption.
FORBES: Mark Coker: Significant Disruption For Traditional Publishers Still To Come
"It is reasonable to assume that there will be some significant disruption to European air traffic tomorrow, " Deputy Head Brian Flynn told reporters.
Union officials say the move has been "pushed through" with little or no consultation and warned of "significant disruption" as a result of the work-to-rule.
The agency said a band of rain sat across the region from York to Durham for much of the day, bringing with it "significant disruption".
Finally, hiding messages widely amid otherwise-legitimate content makes it difficult for a censor to block communication effectively without also causing significant disruption to innocuous users.
He added that the company does not think a significant disruption in production as a result of the recent earthquake and tsunami in Japan is likely.
The European air traffic agency Eurocontrol said the ensuing chaos was worse on Friday than the previous day, and warned of "significant disruption" to air traffic on Saturday.
Hertfordshire Police said the party caused "significant disruption" to operations.
BBC: Facebook party: Hertfordshire man admits public nuisance
However, the raft of call-offs means a second weekend of significant disruption in Scottish football - with seven SFL and Scottish Cup games having also been postponed on Tuesday.
According to the British Airport Authority (BAA), which operates many of the UK's major airports, the adverse weather has caused significant disruption to airports in the south-east of the country in particular.
And the news is not good: the MLR regulations are likely to lead to a significant disruption of the health insurance market, with many insurers exiting the market, driving premiums up and choices down.
Thus, to answer the question, mitigating the effects of the eruption will require preparations to protect human life, and to prepare the nation and economy for the inevitable significant disruption and damage that follows the eruption.
FORBES: What Can Be Done To Mitigate The Effects Of The Looming Mt. Fuji Eruption?
Guaranteeing that people can get coverage regardless of their health "would cause significant disruption and skyrocketing costs unless all Americans have coverage, " said Robert Zirkelbach, a spokesman for America's Health Insurance Plans, an industry trade group.
"We may experience a significant disruption in the supply of fabrics or raw materials from current sources or, in the event of a disruption, we may be unable to locate alternative materials suppliers of comparable quality at an acceptable price, or at all, " the company said in the filing.
Motorists were told there was a risk of significant travel disruption through the night and on Saturday morning.
The IEA is prepared to act when there is a significant supply disruption or an imminent threat thereof.
He said there was a risk of significant travel disruption through Friday night and the first part of Saturday.
However, disruption remained significant with millions of people affected by the walkout.
The obvious conclusion is that we are massively dependent on a resource that has steady ramping global demand and very concentrated supply, with a significant risk of a disruption of this supply.
FORBES: A National Imperative -- Building an Interstate Network of Toilets
On this occasion, the most significant reason given for the disruption was that it was the first major weather event since the introduction of alternate weekly refuse collections.
BBC: Household rubbish piled up outside a house in Cheltenham
Particularly in a tightening market such as the one we see currently, a relatively small disruption can have a significant impact on the market.
And the disruption of this plot represents a significant achievement by our intelligence and law enforcement agencies.
If the goal is to bring our government spending more in line with what we can afford, we need to mange this over a significant period of time or risk serious economic disruption.
FORBES: Fiscal Cliff Deferred, Tax Legislation Is only Part of the Equation
应用推荐