Big selling cancer drugs like Rituxan, Avastin and Erbitux are antibodies against signaling molecules that spur tumor growth.

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The new data indicate that leukotrienes, immune-system-signaling molecules previously thought to play a crucial role only in asthma, are also overabundant inside diseased arteries.

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These drugs--such as Herceptin for breast cancer (Genentech) and Erbitux for colon cancer (Eli Lilly)--were designed to bind to signaling molecules on tumors and disrupt cell growth signals.

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