The FDA then did its own study of side effect reports sent in by doctors and patients.
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On the pro sleep-training side, an Australian study published in September followed 326 children with parent-reported sleep problems at 7 months.
The most common side effects reported in the study were: were dizziness (seen in 10.4% of those on Ampyra, 2.5% of those on placebo), nausea (3.9% Ampyra, 6.2% placebo), fatigue (5.2% Ampyra, 3.7% placebo), insomnia (5.2% dalfampridine-ER, 2.5% placebo) and arthralgia (2.6% Ampyra, 3.7% placebo).
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Armitage said that the trial results are unlikely to be due to the side effects of laropriprant, since the main finding of a lack of benefit is consistent with the AIM-HIGH study and many of the side effects are known to be associated with the use of niacin.
Similar questions can be asked about whatever side effect Merck saw in this study.
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The researchers said side effects were mild in the study, whose duration for participants averaged 1.2 years.
The UK trial - in which all eligible children will receive immunotherapy - will attempt to reduce the severe side effects seen in the US study.
Naurex said the main side effects in a Phase IIa study of its GLYX-13 compound with 116 people with depression were headache and sleepiness, similar to the effects of a placebo saline injection.
Food, long believed to be vital to sustaining life, may also have a darker side, according to a recently released study.
So far officials of the National Institutes of Health say they've seen no serious side effects in clinical trials and that study subjects who have been immunized have generated a good response.
While the study is definitely on the small side -- just five patients -- the researchers seem to be quite enthused with their findings, reporting that four of the subjects achieved significant reductions in pain, in one case after just a single session.
No man who can sit in his own study with his telephone by his side, and thus listen to the performance of an opera at the Academy, will care to go to Fourteenth street and to spend the vening in a hot and crowded building.
On the plus side, these records give researchers a chance to study all sorts of social behavior that were mostly invisible before.
ExoMars, as we call it on this side of the pond, envisages a satellite to study the Martian atmosphere, followed by a large robotic rover to drill beneath the surface and cache rocks for later return to Earth.
We couldn't afford to tell those kids on the West Side or the South Side, if you work hard, if you study hard, if you're hitting the books, that you're going to be able to afford to go to college.
In one unusual but revealing study, his researchers repeatedly immersed one side of people's bodies until it showed evidence of habituation, while keeping the other side warm -- and then turned them over and immersed the side that had never been in the cold water and found that there was still a significant reduction in their cold shock response.
In that study, Lipitor did not have the muscle side effects seen in this Zocor trial.
Even the dog's closest relative, the wolf, beat its cousin when food was placed on the opposite side of a fence, as shown in a 1982 study by Harry and Martha Frank of the University of Michigan.
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Mass producing stem cells to screen drugs and study the progress of disease is not the sexier side of the field.
The unexpected study is to check for a common but deadly side effect called QT prolongation, in which the electrical signals that cause the heart to beat are drawn out.
Todd Troost, professor of neurology at Wake Forest, who led the study said Botox could be less expensive and have fewer side effects than many medications used for headache prevention.
In a 2008 study, de Waal and colleagues put two capuchin monkeys side by side and gave them a simple task to complete: Giving a rock to the experimenter.
Patients were tried on the drug before the trial started, meaning those with obvious side effects were screened out, and Crestor was so effective the study was stopped ahead of schedule, limiting the safety data.
German drug giant Bayer failed to tell the U.S. Food and Drug Administration of a study that connected a controversial heart surgery drug to dangerous side effects and death, even as FDA convened a panel of experts to evaluate the drug's safety.
But some heart researchers are pushing back, saying that there is still a role for niacin, albeit a diminished one, and that the study does not allow scientists to tease out whether the side effects were due to niacin or a second drug, laropiprant, that Merck added to prevent the hot, unpleasant facial flushing that is one of the main reasons people often refuse to take niacin.
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Cardiologists on Novartis' study say Prexige does not appear to have any perceivable heart side effects.
However, this new study revealed that the shark is also luminescent on its top side.
In an interview, Yancy said that although the study is not enough to give Natrecor a complete stamp of approval, he thinks the study was well designed to pick up a signal of kidney side effects.
The drugmaker is also conducting a long-term outcomes study to see if any heart- or kidney-related side effects turn up in patients using Cox-189, hoping to forestall any of the safety concerns that have hurt Celebrex and Vioxx.
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