And with Tottenham's Aaron Lennon still suffering from a groin problem, Capello may now turn to both Theo Walcott and Shaun Wright-Phillips to cover the right side of midfield, with James Milner, Joe Cole, Stewart Downing and Adam Johnson also in the reckoning.
Ousmane Ndoye will almost certainly fill in for the suspended Khalilou Fadiga on the left side of the Lions' midfield.
The Suffolk side lined up with the dangerous Connor Wickham on the left side of a five-man midfield as Town successfully stymied their Premier League opponents.
"Jake has been excellent in moving the ball from side to side and controlling the game from midfield alongside Frecklington so it's obviously a loss, " he said.
And, although the early goal visibly rocked Celtic's confidence, the home side began to take control of midfield and Scott McDonald fired just over from 20 yards, while a head flick from Jan Vennegoor of Hesselink drifted just wide.
United's forward pairing were brought off with 15 minutes to go and, with Owen Hargreaves coming on to shore up the midfield, the home side continued to go close as they secured a victory which took them back to the top of the table.
Of the starting line-up against South Africa, eight are the wrong side of 30 - including the entire midfield quartet.
The 17-year-old, who plays in midfield for the Wolves Academy side, has said goodbye to school for a week as he continues his football education.
Bath dealt better with the conditions at a wet Edgeley Park and, with South African fly-half Butch James back in the side, looked full of ideas in midfield.
With skipper Jason White also out with a head injury, Alasdair Strokosch will start his first Test at blind-side flanker while Webster now finds himself in midfield.
Although a little older and perhaps a yard slower, Chelsea's class of 2011 are still a potent outfit and caused Everton problems on the break, as highlighted by the equaliser, even though manager David Moyes' side had the majority of the possession in midfield.
But the U's were swamped in midfield by a well-organised Wrexham side and struggled for chances.
In both games they had looked light in midfield, a serious deficiency for a side so committed to attack.
Jonathan Davies of the Scarlets is likely to be the new man in midfield when Wales coach Warren Gatland names his side on Thursday.
Priestland extended the home side's lead with his third penalty after a huge midfield hit on the impressive Fussell from Sean Lamont.
And with Arsene Wenger's side missing Alexander Song, they struggled to impose themselves in midfield allowing Everton debutant Landon Donovan, in particular, to take advantage.
With players such as Michael and Brian Laudrup in midfield and Preben Elkjaer Larsen in attack, the side were a force to be reckoned with in the late 1980s.
Now though, it is expected the former Lyon player will line up in central midfield alongside club captain Barry Ferguson as the Ibrox side attempt to recapture the championship from rivals Celtic.
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Gilberto has been kept out of the side because Cesc Fabregas and Mathieu Flamini have formed an impressive central midfield partnership to help steer Arsenal to the top of the Premier League.
Hughes took heart from some of his side's performances and thought the best player was in Hibs' midfield.
Everton, with Mikel Arteta their conductor in central midfield, were showing the neater passing play against a Birmingham side looking solid without carrying much of an attacking threat.
Number eight Luke Narraway captained the home side with Mike Tindall on England duty - Jonny May replaced Tindall in midfield - while Brett Deacon faced his former club.
With Dean Keates and Paul Coutts playing well in central midfield, Frecklington will need to work hard to break into the side.
The 22-year-old, who moved to Stamford Bridge from Norwegian side Lyn Oslo in 2006, impressed in the holding role in the Blues midfield last term.
Toshack blamed a lack of consistency in his side and the loss of Aaron Ramsey, Joe Ledley and Dave Edwards from his midfield.
New Wolfsburg coach Veh made just one change from the side preferred by his predecessor Felix Magath last season with Karim Ziani starting in the midfield behind Edin Dzeko and Grafite.
Centre Darren Cave gave the final pass to midfield partner Paddy Wallace, who dived over after 32 minutes for Matt Williams' side to lead 13-3 at the break.
Andre Ooijer, Stephen Warnock, Keith Andrews, Jason Roberts and Pedersen also returned to the side, while Sunderland manager Roy Keane settled for bringing in Teemu Tainio to replace Jordan Henderson in midfield.
The Frenchman, the rock in Arsenal's solid midfield for the past five years, featured in almost every match for Arsene Wenger's side last season.
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