Smith says there have been some preliminary results with antipsychotics, such as Zyprexa, Risperdal and Seroquel.
Nexium, Seroquel (for schizophrenia and bipolar disorder), and Crestor (for high cholesterol) have all been successful.
Eli Lilly ( LLY - news - people ) and Seroquel from AstraZeneca.
And, at low doses, Zyprexa and AstraZeneca's Seroquel are often given as a sleep or calming aid.
Another cause for concern is Seroquel (No. 11), the most popular antipsychotic drug.
AstraZeneca is seeking approval to market Seroquel for treating children, and Eli Lilly is asking for the same for Zyprexa.
Abilify, from Otsuka and Bristol-Myers Squibb, passed Seroquel from Astra as the top-selling antipsychotic drug for disease like schizophrenia, bipolar disorder, and depression.
Risperdal, Zyprexa and AstraZeneca's Seroquel followed in the next seven years.
She has had particular luck with Seroquel in low doses, which has often been used for its sedating effects (see: Antipsychotic Prescribed As Sleeping Pill).
These medications, along with Seroquel, were prescribed for Rebecca after she was diagnosed, at the age of two, with attention deficit hyperactivity disorder (ADHD) and bipolar disorder.
Pharmaceuticals got a small boost from news that gave encouragement that AstraZeneca could have some success in court protecting its patents for the drug Seroquel against generic competition.
Although they are called "antipsychotics, " these agents (for example Seroquel, Abilify, Zyprexa) are also widely used to help with severe depression and anxiety and are often quite effective.
"AstraZeneca hopes to market Seroquel XR to the more than 20 million Americans suffering from depression or anxiety, but its side effects could give regulators pause, " says Moroney.
He was eventually switched to Zyprexa, which caused weight gain, and then to AstraZeneca 's (nyse: AZN - news - people ) Seroquel, another drug used in the CATIE study.
The FDA was facing enormous pressure following controversies like the withdrawal of Merck's painkiller Vioxx, linked to heart attacks, and alleged overuse of anti-psychotic drugs like Zyprexa from Eli Lilly and Seroquel from AstraZeneca.
Pharmaceuticals got a small boost from news that gave encouragement that AstraZeneca (nyse: AZN - news - people ) could have some success in court protecting its patents for the drug Seroquel against generic competition.
Schizophrenics who need the anti-psychotic Seroquel, made by AstraZeneca (nyse: AZN - news - people ), instead may get Bristol-Myers Squibb 's (nyse: BMY - news - people ) depression drug Serzone.
In 2000, Harrell switched again--this time to AstraZeneca 's (nyse: AZN - news - people ) Seroquel on the recommendation of a movement disorder clinic and a doctor who came to one of his jazz shows.
For instance, AstraZeneca's (nyse: AZN - news - people ) Seroquel is often used for its sleep-promoting or calming effect. (see: " Antipsychotic Prescribed as Sleeping Pill") Eli Lilly 's (nyse: LLY - news - people ) Zyprexa has even been used in rare cases in patients with anorexia--one of the drug's potential side effects is weight gain.
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