Among other, serious defects in this legislation is its substitution of institutionally unqualified federal judges for executive branch officials with respect to the task of determining whether source disclosure would be in the 'public interest.

CENTERFORSECURITYPOLICY: Center For Security Policy

It documents how the Obama administration sought to obscure the serious defects in the treaty it had negotiated by pressing the Senate to conduct its advice and consent responsibilities under circumstances that were calculated to render oversight exceedingly superficial and debate cursory, at best.

CENTERFORSECURITYPOLICY: Center For Security Policy

DiGeorge Syndrome has also left Seth with some serious heart defects.

FORBES: Indiana Medicaid Denies Life-Saving Transplant To Baby

Curis, a firm based in Cambridge, Massachusetts, is building complex organs out of adult stem cells and testing them in patients with serious organ defects, such as bladder failure.

ECONOMIST: Stem cells

Recently-delayed approvals include a new drug designed to slow the effects of Lou Gehrig's disease, the french abortion pill RU-486, and new uses for thalidomide, which caused serious birth defects when first introduced in the 1950's.

CNN: FDA delays approval of new diet drug amid cancer concern