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Clinton, 65, now faces persistent questions about whether she will mount a second White House run in 2016 to break perhaps the highest remaining glass ceiling.
CNN: Clinton's farewell marred by embassy bombing
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This is Mr Romney's second run for the White House, after an unsuccessful bid in 2008.
BBC: Mitt Romney becomes Republican presidential nominee
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Edwards ended his second run for the White House yesterday with the promise that Hillary Clinton and Barack Obama would press the issue that was central to his campaign.
NPR: Assessing a Two-Person Democratic Race
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John Kerry, the Democratic presidential nominee in 2004, announced Wednesday that he will skip a second run for the White House to concentrate on bringing the war in Iraq to an end.
CNN: Kerry decides against 2008 presidential run
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But he jokes that he did better in his second run for the White House than he did the first time around when he lost the 2008 nomination to Arizona Sen.
NPR: Romney: Heart Told Him He'd Win, Until He Saw Fla.
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The Arizona senator's campaign -- his second run for the White House -- was largely written off last summer amid outspoken opposition from the party's conservative base, a major staff shakeup and disappointing fundraising.
CNN: McCain wins GOP nomination; Huckabee bows out
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Correspondents say the announcement, which comes weeks after Mrs Clinton left her post as the top US diplomat, is likely to fuel speculation that she may be considering a second run for the White House.
BBC: Hillary Clinton backs gay marriage in online video
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The Arizona senator's campaign -- his second run for the White House -- was largely written off for dead last summer amid outspoken opposition from the party's conservative base, a major staff shakeup and disappointing fundraising.
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