"Our study would strongly suggest that it is not beneficial to do it as front-line treatment but to reserve it as second-line or salvage therapy, " said study leader Dr. Mark Gilbert of the University of Texas MD Anderson Cancer Center in Houston.

NPR: Avastin Fails Studies In New Brain Tumor Patients

"What we do not agree with is that it should be used as a second- or third-line therapy, " says Enrico Veltri, the Schering-Plough vice-president in charge of heart disease drugs.

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