The next speaker after Nissen was Robert Califf, the vice chancellor for clinical research at Duke University.

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Improve It is being conducted by some top researchers, including Harvard University's Eugene Braunwald and Duke University's Robert Califf .

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But those drugs have side effects that make them difficult to take, says Robert Califf of Duke University, who is helping to run the biggest Vytorin study.

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Orexigen says that it has already convened advisers for the trial including Robert Harrington and Robert Califf, both of Duke, and Steven Nissen, of the Cleveland Clinic.

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"I would call this a Bill Buckner type of study, " says Robert Califf, vice chairman for clinical research at Duke University who is leading a big study of Zetia and takes the drug himself.

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"In terms of public health, people who have already had a cardiac event should be on a statin, " added Robert Califf, vice chancellor for clinical research and a cardiologist at Duke University Medical Center.

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The study's good design "provides a basis to infer cause and effect" between poverty and bad health, said Dr. Robert Califf, a noted Duke University cardiologist who is leading a massive study on neighborhoods and health outcomes.

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