In recent months, Lilly-backed researchers have shown that prasugrel's risk-benefit profile looks better in diabetics and patients with certain types of heart attacks.
Bottom line: If, consistent with our base-case expectation, the U.S. averts a recession, equities are inexpensive enough to provide investors with an attractive risk-reward profile.
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In other words, we needed entry and exit and position-size methodologies that would allow us to skew the risk-reward profile, that would allow us to end up with a larger magnitude of profits than losses.
As befits a Swiss bank, UBP keeps an ultra discreet and risk-averse profile, with liquidity exceeding regulatory requirements, but in 2008 it shocked the banking establishment when its clients emerged as major victims of swindler Bernard Madoff.
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Concerned about the entire class of COX-2 inhibitors, the FDA convened a joint session of their Arthritis Advisory Committee and the Drug Safety and Risk Management Advisory Committee on February 16, 17 and 18 to advise the FDA on the risk-benefit profile for these drugs.
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You may see potential for high visibility, but understand this means you risk a high-profile flameout.
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When taking a drug, the benefit-risk profile must be considered.
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"Clearly it brings a level of credibility to what is a high-risk investment profile, given how much work there is to be done and who they're competing against, " he says.
While any unexplained death is worthy of attention, there is a real risk of high-profile publicity driving MS patients away from a convenient, user-friendly treatment that can help them forestall a disabling disease.
Ostensibly, high-profile and high-risk companies may appear to be at greater risk, but small-to-medium sized businesses are not immune.
The fine relates to four structured bonds sold by the bank between January and March with a 'medium-to-low' risk profile instead of 'high'.
The risk profile for emerging-market corporates has improved thanks to stronger sovereign balance sheets and economic growth prospects compared with developed markets, and we believe that emerging-market corporate bonds are an increasingly attractive asset class.
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Surprisingly, real estate--including landlords, agents and developers--has a relatively low risk profile, according to Fair Isaac's data.
It's unclear whether a record of the gun incident or other risk factors -- Chukwu's travel patterns and personal profile -- triggered his secondary screening in Detroit.
The data is then analysed to produce a schematic read-out for immigration officials that shows the risk profile for every single passenger on an incoming flight, seat by seat, high risk to low risk.
The result is a profile of the federal agency most visibly aligned with markets and risk--a story both inspiring and impressive but daunting in its implications for boards of directors and their companies.
The model also enables managers to fine-tune debt portfolios by estimating the effect new assets will have on the overall risk profile.
Both universities, respected in England, but not world-famous, have decided that risk is worth taking in the hope of boosting their global profile.
Initial public offerings and other securities activities have a radically different risk profile than sophisticated buyers and sellers setting the price on a private company in a fully-negotiated transaction.
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Crane, as we wrote in our magazine profile of his creative new-nuke plan, is more comfortable when someone else takes risk.
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