Epothilone has the potential to be even more effective against taxane resistance because it has a different chemical structure that may let it bind better with microtubules.

FORBES: Taxol's Next Stand

Even if they are effective, vaccines may face stiff resistance from parents who are urged to let their 11-year-old daughter or son get a shot against a sexually transmitted disease.

FORBES: Cornering A Killer

Even if they are effective, vaccines may face stiff resistance from parents who are urged to let their 11-year-old daughter get a shot against a sexually transmitted disease or told that their son needs one for a disease that is likely never to harm him.

FORBES: Cornering A Killer

The focus now is on trying to monitor and contain artemisinin drug resistance into a few hotspots, prolonging the drug's effective lifespan globally until alternative treatments are available.

BBC: Can Asia save Africa from drug-resistant malaria?

Then again, bacterial resistance is a prevalent problem, with many drugs becoming less and less effective by the year.

FORBES: FDA OKs Aventis Antibiotic

The first round of Lupron therapy is often effective, but a significant number of patients later develop a resistance to the drug.

FORBES: Can Big Data Save My Dad From Cancer?

Growing drug resistance and changing climates means that older drugs like chloroquine have become less effective and so new generations of drugs like Lariam have been recommended as frontline preventative treatment.

BBC: The anti-malaria drug dilemma

Because if that happens, the Taliban resistance in the mountains will find itself isolated from the people, and unable to reassert any effective political strategy to go along with guerilla raids, and over time, they will become increasingly marginalized.

CNN: James Steinberg: Afghanistan war strategy