Four big-screen, big-budget features, from 1978 to 1987, starred Christopher Reeve as the Man of Steel.

WSJ: The Superhuman Appeal of Superman | By Will Friedwald

The debate about embryonic stem cells was good example: proponents had Christopher Reeve walking, and opponents minimized their potential.

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Singer's new film stars Brandon Routh, who takes over the role following the death of Christopher Reeve in 2004.

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Actor Christopher Reeve put the spotlight on spinal cord injuries after he was paralyzed in 1995 in a riding accident.

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In 1978 when Christopher Reeve filled Superman's red boots, technology had advanced to make Superman look a little more realistic.

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Thirty-four years later, it remains one of the most perfect superhero origin stories put to film, and Christopher Reeve is still one of the most brilliant casting choices of the genre (this is really the only film that rivals the casting of Robert Downey Jr. as Iron Man).

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We passed the Christopher and Dana Reeve Paralysis Act -- the first piece of comprehensive legislation aimed at addressing the challenge faced by Americans living with paralysis.

WHITEHOUSE: President Obama Signs 21st Century Communications & Video Accessibility Act | The White House

That's the mission of the Christopher and Dana Reeve Foundation.

WHITEHOUSE: President Obama Signs Major Public Lands Protections