The winger's probing low cross from the right was missed by the Greek defence and the ball rebounded to Novo, who lashed the ball into the corner of the net.
Danish goalkeeper Christiansen attempted to punch away McGeady's dangerous cross but the ball rebounded off Keane's back and into the net.
BBC: SPORT | Football | Internationals | Denmark 0-4 Republic of Ireland
The ball rebounded back out and the United captain fired in an unstoppable shot from 25 yards into the corner of the net.
Stephen Jones put in a try-saving tackle on his rival fly-half but the ball rebounded off the Scarlets man into touch and the Ospreys had a five-metre attacking line-out.
"It is surprising to me that this has happened, " said the 30-year-old Vancsik, who rode his luck when his ball rebounded off a cart path on the 10th when it should have gone out of bounds.
First Donovan's shot was brilliantly saved by M'bolhi but when the ball rebounded to the attacker, he quickly squared it to Dempsey, who turned it into the net, only to see his celebrations thwarted by the linesman's flag.
Alexander, who replaced regular first-choice goalkeeper Allan McGregor as per the previous rounds of the competition, wanted too much time with a backpass and was almost caught by Jack Ross but the ball rebounded out for a goal-kick.
Electing to tackle the Honduran's cross with his legs, the normally reliable Jaaskelainen - who had pulled off a fine save from Defoe only moments earlier and was again under pressure from the England man - failed to make contact and the ball rebounded in off his standing leg.
De Villiers was again reprieved by Harper on an lbw appeal shortly afterwards, but this time the ball was clearing over the stumps and there could be few complaints, although luck remained on the batsman's side - the ball spun on to his stumps but rebounded without dislodging the bails.
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But it all stopped after a sequence in which Crosby made a steal and her left-handed layup missed, Franklin rebounded and missed twice, the second called a jump ball.
It continued a lean streak for the opener, but replays suggest the ball did not make contact with the bat and instead rebounded off his pad.
Derby missed a couple of opportunities to clear and Vassell crashed the ball home from six yards after Neil Danns' powerful strike rebounded off the foot of the post.
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