Obamacare and Dodd-Frank contain reams of Byzantine regulations which are largely either still being defined, or subject to interpretation by cabinet leaders reporting directly to the president.

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To this day, there are still places in the federal government where reams of yellow files in manila envelopes are walked from desk to desk, or boxes of documents are shipped back and forth between offices because files aren't yet online.

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Toward this end, Merck (nyse: MRK - news - people ) recently bought biotech boutique Rosetta InPharmatics, which employs astrophysicists and engineers to crunch reams of gene data to spot telltale patterns that help predict if a drug will perform as promised or might have intolerable side effects.

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Reams of research point to the same finding: physicians looking at the same thing will disagree with each other, or even with themselves, from 10 percent to 50 percent of the time during virtually every aspect of the medical-care process from taking a medical history to doing a physical examination, reading a laboratory test, performing a pathological diagnosis and recommending a treatment.

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