Other drugs, like the old cholesterol-lowerer Questran, also block sterols, says Sam M.

FORBES: The Vytorin Saga

In a 1984 study, lowering LDL 12% with the Bristol-Myers Squibb drug Questran showed a benefit only after seven years.

FORBES: Magazine Article

In a 1984 study, lowering LDL 12% with the Bristol-Myers Squibb (nyse: BMY - news - people ) drug Questran showed a benefit only after seven years.

FORBES: The Statin Showdown

Christie Ballantyne of Houston's Baylor College of Medicine says he thinks using resin drugs like Questran or WelChol before Zetia doesn't make much sense, because those medicines are so inconvenient that patients won't stay on them.

FORBES: How Low Can Vytorin Go?