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The gene forces the body into producing too much of an immune system protein called interleukin-1.
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The vaccine, called Stimuvax, aims to stimulate the immune system to attack a protein fragment called MUC-1 found on lung, breast, prostate and colon tumors.
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Some 30% to 40% of melanoma tumors contain a rare protein called NY-ESO-1 that looks suspicious to the immune system.
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The American College of Sports Medicine recommends that endurance and strength training athletes consume higher levels of daily protein than the standard recommended daily allowance (i.e. 1.2-1.7 grams of protein for each kilogram of body weight, versus 0.8 grams per kilogram per day).
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What they have found is that about 1, 800 protein-coding genes, some 7% of the total known, show signs of having been subject to recent natural selection.
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University researchers had just pinpointed a source: a bad gene that causes the body to produce an oversupply of interleukin-1, an immune system protein.
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LINE-1 jumped to a location in the genome near PSD-93 it increased production of the protein.
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Protein-kinase genes, whose products are involved in intracellular signalling, are similarly concentrated on chromosome 1.
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