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The original version contained at least five times the estrogen that it does today, and ten times the progestin.
CNN: Health - Look what's 40 -- the pill
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The morning-after pill contains a higher dose of the female progestin hormone than is in regular birth control pills.
WSJ: Obama faces choice on morning-after pill limits
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The study did not find any differences in women taking estrogen and progestin compared to those taking only estrogen.
CNN: Health - Hormone replacement may influence mammography accuracy
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With the reduction in estrogen and progestin, these problems have significantly decreased.
CNN: Health - Look what's 40 -- the pill
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Unless estrogen is given with progestin (the two hormones are combined in the Prempro pill), it may hike the risk of uterine cancer.
FORBES: Wyeth Lucks Out On Hormone Study
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The drug works by using high doses of the female hormone progestin, which also is contained in birth-control pills, to block a potentially fertilized egg from becoming implanted in a woman's uterus.
WSJ: Judge Eases Restrictions on Plan B Emergency Contraceptive
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Data from the Women's Health Initiative and other large-scale trials suggest estrogen plus progestin therapy moderately reduces risk for fractures but increases the chance of developing strokes, dementia, deep vein thrombosis, urinary incontinence and gallbladder disease.
CNN: Government panel: Hormone therapy 'not recommended'
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The drug works by using high doses of the female hormone progestin, which also is contained in birth-control pills, to prevent ovulation or block a potentially fertilized egg from becoming implanted in a woman's uterus, according to the drug's label.
WSJ: Judge Eases Restrictions on Plan B Emergency Contraceptive
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"Another apparently paradoxical finding is that estrogen and progestin impart a small increase in the risks for developing and dying from breast cancer, whereas estrogen alone appears to slightly reduce these risks, " according to the U.S. Preventive Services Task Force document outlining the draft recommendations.
CNN: Government panel: Hormone therapy 'not recommended'