Enhancement biotechnologies have the potential to profoundly impact human and animal life as we know it.
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And climate change has already started to profoundly impact the availability, distribution, and quality of water.
The outcome of this contest will profoundly impact the kind of country the U.S. is going to be.
Secondly, if unemployment insurance were abolished altogether, this would profoundly impact the willingness of the average American to save for a rainy day.
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With this data in your hip pocket, you can not only demonstrate performance gains across search but can also profoundly impact every facet of marketing communications!
At the time nobody imagined that, in addition to her role as a social lioness and hostess to the powerful, she was simultaneously responsible for setting in motion a process that would profoundly impact the outcome of the Afghan war.
Violent conflict has a profoundly negative impact on the planet, even when it occurs in remote places.
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Sometimes largely overlooked, obscure happenings in Congress can have a profoundly positive impact.
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"Whether it's an old contract or not, it has a profoundly negative impact on the balance of interests and the stability of the region, and it does put Israel at risk, " he said.
Yet, what is startling in all of this, besides the fact that each and every one of them has had a profoundly disruptive impact on what was then the status-quo ante thinking of their time, is that such experiences are not typical of what we see today in large, mature organizations, where fresh new ideas are often so scarce.
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The argument is that, over the past three decades, financial markets have changed profoundly under the impact of technology, innovation and deregulation.
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But regardless of his rationale, Zanuck was profoundly mistaken on the significance and impact of television.
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The impact on IPOs was profoundly negative.
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"To stand up and say that we in this country will benefit from climate change profoundly misunderstands the nature of the threat and the impact that climate change is going to have, " he warned.
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