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There is a lot a person can do to help prevent a heart attack.
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Just treating those people, the number needed to treat to prevent one heart attack drops to 37 from 46, and the number of people you need to treat before someone has a major bleed rises to 200 from 167.
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Osiris Therapeutics of Baltimore has several trials under way using adult stem cells to treat the intestinal inflammation known as Crohn's disease, repair damaged tissue following a heart attack and prevent the progression of arthritis.
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The object was to test whether treating patients early and aggressively with a cholesterol-lowering drug would prevent them from having a second heart attack, having a stroke, returning to the hospital or dying.
FORBES: Cholesterol Study Poses Dangers For Merck
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In practice, fish oil pills are used fairly frequently in patients who have had a heart attack to try and prevent future problems.
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It isn't desirable to cause a heart attack in the name of trying to prevent one.
WSJ: Predicting Who Will Have Heart Attacks
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In his JAMA commentary, Nissen writes that Pfizer's drug may help prevent heart attacks not only by lowering bad cholesterol but also by cutting another heart attack risk: inflammation in the arteries.
FORBES: Cholesterol Study Poses Dangers For Merck
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In December, Pfizer said that a government-funded study testing whether Celebrex could prevent colon polyps instead showed that long-term use of Celebrex doubled the risk of heart attack and stroke.
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This is a medicine to prevent heart attacks and strokes in patients who suffer acute coronary syndrome, the condition that occurs after a heart attack or serious heart-related chest pain.
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Low-dose aspirin is already recommended to cut the risk of heart attack and stroke, but there are no national guidelines on who should consider taking it to prevent cancer, or how much to take.
BBC: Aspirin a 'no brainer' against cancer after screening