"For example, hiking in a rural area of the Indian subcontinent where dogs commonly roam free carries a sufficient risk of exposure - combined with potential difficulties in obtaining early, safe and effective post-exposure prophylaxis - to warrant vaccination before travelling, " he said.

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And, with two NIH-funded Stage IIB trials starting at Drexel University soon, the hope is that PRO 140 can eventually be developed into an effective post-exposure therapy delivered via injection once a week or a few times a month versus the current cocktail of pills available to patients today.

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