Instead of targeting thrombin directly, SCH 530348 blocks the receptor that thrombin triggers on platelets.

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Drugs like aspirin and clopidogrel (Plavix, NYSE:BMY) prevent platelets from clumping together into a clot.

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Suppress the prostoglandins in platelets, therefore, and you suppress the formation of the sort of clots that trigger heart attacks and strokes.

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The sample is incubated with platelets and exposed to repeated rounds of ultrasound, which break the prions up into more numerous smaller particles.

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The fibrinogen turns into fibrin, an insoluble, filamentous protein which traps the platelets and causes them to link up into a quilt that helps stop bleeding.

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In fact, under these conditions Viagra caused the platelets to clump together at concentrations well below those found in patients prescribed the drug as an impotence treatment.

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The effects of aspirin were independent of age, and sex, and were also seen with a low-dose, slow-release formulation of aspirin designed to inhibit platelets but to have little systemic bioavailability.

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Her platelets dropped and her white-cell count remained elevated.

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Nitric oxide effectively stops the platelets sticking together.

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